A quick post about a puzzle called Wordle that is currently taking over the internet. It’s a mastermind-like game where the object is to guess an unknown 5-letter word. Puzzlers are encouraged to share their results after completing a puzzle. Here is an example for puzzle 192. So how do you know if your performance on today’s puzzle was any good? Why not benchmark your effort against the crowd?

As 2021 draws to a close, it’s time to check back in on a previous post. As a recap, Garmin Connect offered four challenges to run 3 x 505 km and 1 x 505 km, one in each of the four quarters of 2021. Completing all four would mean running 2021 km in 2021 . I used an R script to check my progress throughout the year (available here). Each quarter gave a set of results, the final set for the whole of 2021 is shown here.

The scientific response to the COVID-19 pandemic has been astounding. Aside from efforts to generate vaccines, the genomic surveillance of the virus has been truly remarkable. For example, the nextstrain project has sequence many SARS-CoV-2 genomes. In fact, the rapid identification of multiple new strains and mutations by diverse groups of scientists has resulted in a nomenclature crisis.

Many running races and events have been cancelled or disrupted due to the pandemic. To fill the void, I’ve been taking on Garmin’s “Challenges”. In Garmin Connect, you can accept a challenge set by Garmin (I think users can challenge each other too). Completion of these challenges gives the user points, which I’ve become somewhat obsessed with.

During the pandemic, many virtual seminar programmes have popped up. One series, “Motors in Quarantine”, has been very successful. It’s organised by my colleagues Anne Straube, Alex Zwetsloot and Huong Vu. Anne wanted to know if attendees of the seminar series were a fair representation of the field. We know the geographical location of the seminar attendees, but the challenge was to find a way to examine research activity at a country level.

I am giving a talk next week and wanted to update some plots from an old analysis that previously featured on quantixed. The question is: how long does it take for a paper get published? The answer is complex (as previously discussed on quantixed), but we can at least find out using data from PubMed what journals declare as the time from when a paper is received to when it was published. The code is below and can be found here.

When a preprint is uploaded to bioRxiv, it undergoes screening before it appears online. How long does it take for Affiliates to screen preprints at bioRxiv? tl;dr I used R to look at bioRxiv screening times. Even though bioRxiv has expanded massively, screening happens quickly (in about 24 h). I am a bioRxiv Affiliate – one of the people who does the screening. Preprints wait in a queue to be screened.

As part of the series on development of early career researchers in the lab, we spent three sessions over three weeks learning the basics of R. In my book “The Digital Cell”, I advocate R as the main number-crunching software but the R literacy in my lab is actually quite mixed. In order to know how to pitch the training, I conducted a quick poll in our lab Slack workspace to find out what R skills people in the lab already had.

How can we contribute to the development of early career researchers in a lab environment? I’m talking about how people in the lab acquire “soft skills” or “get better” in ways that are parallel to doing research. This sort of training can get overlooked in the chase for new results and the excitement of doing biomedical research. I’m testing out a strategy to develop the skills of people in the lab. It’s an experiment.

This post follows on from the last post on BBSRC Responsive Mode funding. Another frequent question from applicants is: “How much can I ask for?” One answer is: the same amount as successful grants. This information is freely available and can be downloaded from the UKRI website. All awarded grants can be searched (even those that have completed) using their database.