We have an analysis routine for proteomics data written for IgorPro. One output is a volcano plot . These plots show the fold change in one sample compared to another and plot that against a p-value to estimate how reproducible any changes observed are. This post is not about that software, but on the topic of how we can recreate this plot in R . What steps need to be considered?

The Center for Antibody Technologies headed by Professor Andreas Laustsen-Kiel (Technical University of Denmark) used high-throughput methods to systematically analyze the venoms of the 26 most deadly snakes in sub-Saharan Africa. The results are now published in Gigascience . Each year, around 500,000 people in sub-Saharan Africa suffer from snake bites, causing an estimated 7,000 to 20,000 deaths.

Giardia, a protozoan parasite which people typically pick up through drinking infected water or contaminated food, can cause diarrhoea and stomach pains.