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Quintessence of Dust

Quintessence of Dust explores science, society, and human nature, focusing on genetics, development, evolution, neuroscience, systems biology, and topics related to scientific literacy. I occasionally discuss intelligent design, creationism, science denial, and other political/social influences on scientific literacy. Additional topics: philosophy, baseball, scientific culture, and Shakespeare. My main theme is scientific explanation.
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Published
Author Stephen Matheson

Defenders of intelligent design theory often dwell on the topic of "junk DNA," which has been molded into a masterpiece of folk science. The ID approach to "junk DNA" involves a fictional story about "Darwinism" discouraging its study, and a contorted and simplistic picture of a "debate" about whether "junk DNA" has "function." The fictional story is ubiquitous despite being repeatedly debunked.

Published
Author Stephen Matheson

Given that disputes over the existence and meaning of the phylotypic stage and the hourglass model have simmered in various forms for a century and a half, the remarkable correspondence between the hourglass model and gene expression divergence discovered by Kalinka and Varga and colleagues would be big news all by itself. But amazingly, that issue of Nature included two distinct reports on the underpinnings of the phylotypic stage.

Published
Author Stephen Matheson

The controversy about the existence of the phylotypic stage is more than some bickering about whether one blobby, slimy fish-thing looks more like a Roswell alien than another one does. It's about whether the phylotypic stage means something, whether it tells us something important about development and how developmental changes contribute to evolution.

Published
Author Stephen Matheson

Thinking about fitness landscapes can stimulate detailed discussion and consideration of the meanings and limitations of such metaphors, and my introductory comments at The Panda's Thumb did just that. Most notably, Joe Felsenstein pointed us to the various ways these depictions can be employed, and urged everyone to use caution in interpreting them.

Published
Author Stephen Matheson

Consider these not-so-random samples from the animal world: a cockroach, a zebrafish, a mouse. What do these creatures have in common? Left to right: American cockroach (Periplaneta americana), zebrafish (Danio rerio), house mouse (Mus musculus). Cockroach image from Wikimedia Commons, zebrafish and mouse from Wellcome Images. Well, they're all animals and that means they're all eukaryotes, for example. They all have DNA-based genomes.