In this post I’ll describe a computational method for splitting two sides of a cell biological structure. It’s a simple method that relies on principal component analysis , otherwise known as PCA.

The newly created Early Career Ecologist Section of the Ecological Society of America is to organizing a mentoring program for the upcoming ESA meeting in Baltimore. ESA can be a big and intimidating meeting for students and postdocs. Let’s face it, many of us are socially awkward and meeting new people can be hard – especially if the people you want to meet are more senior.

We have a new paper out! You can access it here. The work was mainly done by Cristina Gutiérrez Caballero, a post-doc in the lab. We had some help from Selena Burgess and Richard Bayliss at the University of Leicester, with whom we have an ongoing collaboration. The paper in a nutshell We found that TACC3 binds the plus-ends of microtubules via an interaction with ch-TOG. So TACC3 is a +TIP.

When I started this blog, my plan was to write about interesting papers or at least blog about the ones from my lab. This post is a bit of both. I was recently asked to write a “Journal Club” piece for Nature Reviews Molecular Cell Biology, which is now available online. It’s paywalled unfortunately. It’s also very short, due to the format. For these reasons, I thought I’d expand a bit on the papers I highlighted.

Back of the envelope calculations for this post. An old press release for a paper on endocytosis by Tom Kirchhausen contained this fascinating factoid: The equivalent of the entire brain, or a football field of membrane, is turned over every hour If this is true it is absolutely staggering. Let’s check it out. A synaptic vesicle is ~40 nm in diameter.

A couple of months ago Micah J. Marty and I had a twitter conversation and subsequent email exchange about how citations worked with preprints. I asked Micah if I could share our email discussion since I thought it would be useful to others and he kindly said yes. What follows are Michah’s questions followed by my responses. At the level of the journal nothing happens.

This is a guest post by Elita Baldridge (@elitabaldridge) I am currently the remotely working member of Weecology, finishing up my PhD in the lower elevation and better air of Kansas, while the rest of my colleagues are still in Utah, due to developing a chronic illness and finally getting diagnosed with fibromyalgia.  The relocation is actually working out really well.  I’m in better shape because I’m not having to

Last week, ALM (article-level metric) data for PLoS journals were uploaded to Figshare with the invitation to do something cool with it. Well, it would be rude not to. Actually, I’m one of the few scientists on the planet that hasn’t published a paper with Public Library of Science (PLoS), so I have no personal agenda here. However, I love what PLoS is doing and what it has achieved to disrupt the scientific publishing system.

I am incredibly excited to announce that I am the recipient of one of the Moore Foundation’s Investigators in Data-Driven Discovery awards. To quote Chris Mentzel, the Program Director of the Data-Driven Discovery Initiative: I feel truly honored to have been selected. All the finalists that I met at the Moore Foundation in July were amazing as were all of the semi-finalists that I knew. I did not envy the folks making the final decisions.

So here it is, the first of the positions we’ll be advertizing as part of our move to the University of Florida. The official ad is below, but a few comments first. The position is for a student to work with me, but for those who aren’t really familiar with our groups, it’s important to note that my group works closely with Ethan White’s lab (we provide desk space that mixes the labs together, we have a single group lab meeting,