Editors: Mark Wass (University of Kent, UK), Iddo Friedberg (Miami University, Oxford, Ohio, USA), Predrag Radivojac (Indiana University, Bloomington, Indiana, USA) To tie in with the upcoming Automated Function Prediction Special Interest Group (AFP-SIG) at the ISMB/ECCB 2013 meeting in Berlin, GigaScience and the organisers are launching a call for submissions to a thematic series of research from the