It has been almost 10 years now that we have come to the realization that a particular type of our operant experiments can be classified as motor learning. In such “operant self-learning” experiments, the animal learns about the consequences of its own behavior and adjusts future behavior accordingly.

In a discussion about what decisions are, John Krakauer emphatically pronounced that “decisions happen for reasons”, in answering ‘no’ to my question if it wasn’t a decision with which foot to start walking from a stand-still. A recent article from the laboratory of Carolina Rezaval in Birmingham studied a decision-making process in male Drosophila fruit flies where the reasons for each decision seemed apparent.

I was very excited when our latest research paper came out, after all, I was confident our 30-year-long search for the sites of plasticity in the form of motor learning we study was coming to an end. In this work, we were fairly confident that underlying the type of learning we study was a novel form of plasticity in a very specific set of motor neurons in the ventral nerve cord of the flies we use for our research.

We are looking for a PhD student interested in the functional, molecular and structural profile of neuronal circuits underlying learning, memory and behavior. In a 30-year research effort (lay summary, paper), we have recently identified a new gene (atypical PKC, aPKC) necessary for a form of motor learning in the fruit fly Drosophila and in which neurons it is required.

A few years ago, I came across a cartoon that seemed to capture a particular aspect of scholarly journal publishing quite well: The academic journal publishing system sure feels all too often a bit like a sinking boat.

It was my freshman year, 1991. I was enthusiastic to finally be learning about biology, after being forced to waste a year in the German army’s compulsory service at the time. Little did I know that it was the same year a research paper was published that would guide the direction of my career to this day, more than 30 years later. Many of the links in this post will go to old web pages I created while learning about this research.

You may have seen a neutered version of this post over at the LSE blog. This post below, however, puts the tiger in the tank, as it was enhanced by CatGPT: Maybe scholarly societies have taken “the instruction“follow the money!” a tad too literally?

The DFG is a very progressive and modern funding agency. More than two years ago, the main German science funding agency signed the “Declaration on Research Assessment” DORA.

It’s the time of the year again where 30,000 neuroscientists head to the US to talk neuroscience. This year the big annual conference is in Washington, DC, one of the three cities able to host this large event. Our first poster will be up on Tuesday morning and shows results from operant self-stimulation experiments using optogenetics and dopaminergic neurons.

No matter how well-intended (and we all know to which place the road leads that is paved with good intentions!), transformative agreements (such as DEAL in Germany) are generally the wrong tool at the wrong time for making publicly funded science accessible to the public.