Interesting ChemistryReaction MechanismDiastereotopicSpectroscopyTetrahedral IntermediateChimicaInglese
Pubblicato in Henry Rzepa's Blog
Autore Henry Rzepa
The tetrahedral intermediate is one of those iconic species on which the foundation of reaction mechanism in organic chemistry is built. It refers to a (normally undetected and hence merely inferred) species formed initially when a nucleophilic reagent attacks a carbonyl compound. Its importance to understanding the activity of enzymes cannot be overstated.