I talk a lot about building tools that make it easy capture all the objects that we create as part of the research process and then connect all of these up together. Thus far there have been small and limited demonstrators. This is a proposal to build something that demonstrates the general principle at this coming weekend’s Science Hack Day in London.

…but being straightforward is always the best approach. Since we published our paper in PLoS ONE a few months back I haven’t been as happy as I was about the activity of our Sortase. What this means is that we are now using a higher concentration of the enzyme to do our ligation reactions. They seem to be working well and with high yields, but we need to put in more enzyme.