GigaScience recently published an article all about a Genotype Investigator for Genome-Wide Analyses, alternatively known as Gigwa. But what is this and how can it help? Guilhem Sempere explains more in a guest post. Exploring the structure of genomes and analyzing their evolution is essential to understanding the adaptation of organisms to biotic and abiotic environments.

The software application PLINK is one of the most widely used tools in bioinformatics, particularly for genome-wide association studies (GWAS) that look at genetic variants in different individuals to see if any variant is associated with a trait. With the advent of the thousand dollar genome, the computational demands being made on such programs are exploding.