Here’s a fascinating and worrying news story in Science: a top US researcher apparently falsified a lot of images (at least) in papers that helped get experimental drugs on the market — papers that were published in top journals for years, and whose problems have only recently become apparent because of amateur sleuthing through PubPeer. I’m going to wane philosophical for a minute.

Ya casi se termina el año y hay que entregar informes finales. Estas son algunos de los productos que realizamos durante el 2024, vale la pena decir que todos están publicados en acceso abierto pues es una de las filosofías que promovemos, y la mayoría son en español debido a nuestro compromiso de promover la ciencia en nuestro idioma.

Michael in a comment here on the mechanism of the Masamune-Bergman reaction notes that when it occurs as part of the Calicheamicin (an antibody-drug conjugate or ADC) version of this mechanism, a pre-step is first necessary. As discussed in this review article,[cite]10.3390/ph14050442[/cite] the trisulfide linkage is reduced and the resulting thiolate undergoes a facile 1,4-addition to the adjacent enone.

(please cite as https://doi.org/10.59350/zme5j-0jp45) I previously wrote a blog post, “There’s no such thing as sustainable research software,” trying to be somewhat provocative. In it I wrote: However, after thinking about this a bit more, I don’t think this means we shouldn’t try.

Just a placeholder to mark the ongoing impact of the Internet Archive being attacked (see here, here and here for details). The impact of this on the Biodiversity Heritage Library (BHL) has been huge, and reveals the extent to which BHL depends on the Archive.

A growing trend of keeping mongooses as pets in Jamaica has raised alarms among wildlife experts and animal rights activists. While these small carnivores may seem like intriguing pets, several concerns surround their domestication and the potential ecological consequences. Understanding the Mongoose Mongooses are small to medium-sized mammals belonging to the family Herpestidae.

Exploring Colorado’s Emerging Wolf Hot Spot Colorado is at the forefront of an ecological phenomenon as wolves begin to establish a significant presence in parts of the state. While the resurgence of this magnificent predator is a testament to successful conservation efforts, it also raises significant concerns among ranchers.

Once again, we’re looking to grow our editorial team at JOSS! Since our launch in May 2016, our existing editorial team has handled nearly 4100 submissions (~2700 published at the time of writing, 340 under review) and the demand from the community continues to be strong. JOSS now consistently publishes 40-45 papers per month, and this is gradually increasing.

Reutilización CC BY 4.0

Parte I por Guadalupe Gómez-Aguado de Alba Las sociedades de ayuda mutua o mutualistas se desarrollaron en Europa y en América Latina a lo largo del siglo XIX y fueron una respuesta al liberalismo individualista que predominó como proyecto político en las sociedades modernas.