I have been doing paper of the day (#potd) again in 2014. See my previous post about this. My “rules” for paper of the day are: Read one paper each working day. If I am away, or reviewing a paper for a journal or colleague, then I get a pass. Read it sufficiently to be able to explain it to somebody else, i.e. don’t just scan the abstract and look at the figures.

I was lucky enough to attend the announcement made in 2012 of the discovery of the Higgs Boson. It consisted of a hour-long talk mostly about statistics, and how the particle physics community can only claim a discovery when their data has achieved a 5σ confidence level. This represents a 1 in 3.5 million probability of the result occurring by chance. I started thinking: how much chemistry is asserted at that level of confidence?

A great quote from a classic paper by J.B.S. Haldane “On Being The Right Size” (1926). You can drop a mouse down a thousand-yard mine shaft; and, on arriving at the bottom, it gets a slight shock and walks away, provided that the ground is fairly soft. A rat is killed, a man is broken, a horse splashes. The paper is available here. — The post title is taken from ‘Falling and Landing’ by The Delgados from their LP ‘Domestiques’.

Books about the MRC Laboratory of Molecular Biology are plentiful. If you haven’t read any, the best place to start are the books written by some of the Nobelists themselves: “I Wish I’d Made You Angry Earlier” by Perutz, “My Life in Science” by Brenner.

#paperoftheday #potd A common complaint from other PIs is that they “don’t read enough any more”. I feel like this too and a solution was proposed by a friend of a friend*: try to read one paper per day. This seemed like a good idea and I started to do this in 2013. The rules, obviously, can be set by you. Here’s my version: Read one paper each working day.