Interesting ChemistryImmediate ProductInversionReaction MechanismTriflate LeavingCiencias QuímicasInglés
Publicado in Henry Rzepa's Blog
Autor Henry Rzepa
The reaction described in the previous post (below) is an unusual example of nucleophilic attack at an sp 2 -carbon centre, reportedly resulting in inversion of configuration[cite]10.1021/ja00765a062[/cite]. One can break it down to a sequence of up to eight individual steps, which makes teaching it far easier. But how real is that sequence?