A Matryoshka doll is better known as a Russian nesting doll. They can have up to eight layers. Molecules can only emulate two layers, although see here for a good candidate for making a three-layered example (the inside layer is C ₆₀ , which itself might encapsulate a small molecule. See also  DOI: 10.1021/ja991747w). These molecular dolls can be created out of quite simple molecules.